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V, T., & Veerareddy, P

The reaction is procedurally simple and offers limited chemoselectivity, as aromatic amines were found to be unreactive

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Steere AC, McHugh G, Damle N, Sikand VK

In order to prevent this phenomenon, catalase (another antioxidant enzyme) which is abundant in the peroxisomes breaks down H 2 O 2 into water and molecular oxygen, consequently curtailing free radical-induced damage ( 2 O 2 to water and lipid peroxides to their corresponding alcohols is carried out by Glutathione Peroxidase (GPx)

Not because the risk is high in a healthy adult without a cancer history, but because the consequence of missing a contraindication is high enough that the screening is worth doing without exception