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B.MinutiA.TrevisiE.LuchiniD

Reprogramming cellular metabolism presents another option to adjust ferroptosis sensitivity

CrossRef Development of a technology-enhanced patient-reported outcome evaluation system for inflammatory bowel disease: A multidimensional approach to assessing survival quality Qian Jiang, Ling Du Technology and Health Care.2025;[Epub] CrossRef IBD-PODCAST Spain: A Close Look at Current Daily Clinical Practice in IBD Management P

BBBblood-brain barrier

Frontiers in Aging Neuroscience, 8 , 276.

In the liver, ER stress and UPR activation, particularly the IRE1 branch, mediate the adaptive metabolic shift towards fatty acid oxidation and ketogenesis under fasting and KD conditions, while in the context of aging and disease (ischemia, low glucose and diabetes) the KD and BHB treatment down-regulate ER stress supporting proteostasis and preventing inflammation and cell damage in the liver, retina and brain