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Do not forget nephrotic syndrome as a cause of increased requirement of levothyroxine replacement therapy

Following absorption, Hg 2+ is transported via the bloodstream to the kidneys, where it accumulates predominantly in proximal tubular epithelial cells, making the kidney the primary target organ of its toxicity

Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer

Potential therapeutic targets are low-grade systemic inflammation, oxidative stress, NO signaling, RAAS signaling, ECM remodeling, calcification, VSMCs, and cellular senescence

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