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This is due to its antioxidant properties, which can interfere with the oxidative damage that chemotherapy drugs aim to induce in cancer cells

Stacking two appetite-active compounds can amplify them, which is the single biggest tolerability concern with any cagrilintide-plus-tirzepatide concept

No treatment-related adverse events or tolerability issues were observed

Therefore, although substance P is expected to induce antitumor immune responses, it can also promote tumor metastasis, at least in mouse models of breast tumors