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Plant Cell 17:268281 del Ro LA, Corpas FJ, Sandalio LM, Palma JM, Gmez M, Barroso JB (2002) Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes

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found that rotenone (a respiratory chain inhibitor that can increase mitochondrial ROS and total ROS) induced higher inflammasome activity of NLRP3 compared with lipopolysaccharide, indicating that ROS promoted the initiation step of NLRP3 assembly, and Nrf2 activation-induced NQO1 expression to clear ROS, thus inhibiting NLRP3 expression and subsequent caspase-1 cleavage ( Figure 5 ) (82)

Vitamin D and probiotic cosupplementation affects mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome