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Taking into account that the redox processes are not spontaneous in cells, but the adequate reaction velocity and appropriate specificity are achieved by the catalyzing activity of enzymes, special attention has raised toward the glutathione-utilizing enzymes

The availability of SAMe in hepatocytes leads to phosphatidylcholine production 5

Hepatology 1982, 2: 591-597

: Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight loss

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Moreover, BMAL1 maintains redox balance [52], and mitochondrial function [53, 54]