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For example, in melatonin competent mice (e.g

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Physiol Rev 87:315424 Packer L (1996) Nitric oxide

ODriscoll histological assessment Histological findings ( n = 8 at each time point) for each section were evaluated and scored by three investigators according to ODriscoll histological grading parameters (cell morphology, matrix staining, structural integrity, thickness/defect filling, osteochondral junction, adjacent bonding, basal integration, cellularity, clustering/distribution, and adjacent cartilage) to quantitatively evaluate the extent of cartilage repair based on the criteria of predominant tissue type, structural properties, freedom from degenerative changes in the neighboring cartilage, and freedom from cellular changes of degeneration [26]

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doi: 10.1016/j.ejphar.2023.175875 Summary Keywords ferroptosis, Parkinsons disease, neuronal death, oxidative stress, lipid peroxidation, epigenetics Citation Tu R, Han Z, Zhang H, Jia X, Sun T, Liu H, Li J, Tang M and Wang S (2025) From pathogenesis to treatment: the emerging role of ferroptosis in Parkinsons disease