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The elucidation of antioxidant defense systems in ferroptosis regulation has advanced our integrated understanding of the interplay between iron metabolism and oxidative stress in regulated cell death

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Eur J Neurosci 19(8):20692079 Renna M et al (2013) IGF-1 receptor antagonism inhibits autophagy

Telomerase activation is its signature mechanism: Epitalon can activate telomerase and lengthen telomeres in human cells, extending their replicative lifespan beyond the Hayflick limit, while preserving youthful morphology and function, though this benefit must be weighed against potential cancer risks