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Genes Brain Behav 18(2):e12549

J Comp Med Commun

From a biomedical perspective, significant research directions include understanding and controlling targeting of NPs to the desired location and the role of the biomolecule corona in driving this, as well as understanding and predicting the impact of the biomolecule corona on drug release rates and reducing off-target effects arising from sub-populations of the NPs being bioprocessed or biodistributed differently to the ideal