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Consistent with these findings, both the intracellular Fe 2 + level (pro-ferroptotic) and the glutathione level (anti-ferroptotic) were elevated in CLL cells (Fig

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174 XRCC1, a protein of 69.5 kilodaltons and consists of 633 amino acids (including six cysteines), aids in recruiting proteins for base excision repair by interacting with PARP1, ligase III, APE1, and pol