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A peer-reviewed study of 224 heat-exposed workers tracked micronutrient losses over a single 8-hour shift and found average losses of: sodium 3,725 mg, potassium 514 mg, magnesium 18.4 mg, zinc 0.88 mg, vitamin C 15.7 mg, vitamin B1 0.23 mg, and vitamin B2 0.20 mg (PMC/NIH, 2016)

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2000;279(2):C335-40

This creates a catastrophic bottleneck in the liver

Although our sample was screened for various health conditions (e.g., neuropsychiatric and neurodegenerative diseases), it is possible that some individuals had underlying early-stage pathology that contribute to (neuro)inflammation and/or a longer sleep duration [61]

Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S