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Oxaliplatin downregulates expression of potassium channel Kv2.2 in the somatosensory cortex, thereby requiring a smaller stimulus for neuronal firing (Thibault et al., 2012)

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ii) combination therapy: The synergistic effects of ferroptosis modulators with conventional therapies (such as radiotherapy, chemotherapy and immunotherapy) should be evaluated in preclinical models

The term hemochromatosis itself implies an iron overload of genetic origin