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Comparatively, D2-like receptors D2, D3, and D4 couple to G inhibitory (Gi) proteins, thereby inhibiting adenylyl cyclase to reduce cAMP production

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10.1038/nrn3257 Nat

The blue color is a useful spectroscopic and visual handle for monitoring copper complexation, for assessing the integrity of the complex in solution, and for distinguishing the copper-bound form from the apo-peptide (which is colorless or pale)

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Epicatechin is the isomer with the cis configuration and catechin is the one with the trans configuration