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A high level of Hcy is associated with venous thromboembolism, one of the leading causes of death in cancer patients [144]

after the cold tumors turn hot, immune checkpoint inhibitors (ICIs) or CAR-T therapy are then administered to maximize the synergistic effect

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Like in iron deficiency anaemia, subjects with hypochromic anaemia have higher levels of 2,3-DPG (141) , while the latter decreases in polycythemia (142)