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"Smoking even a small number of cigarettes per day has substantial negative health effects and [the study provides] further evidence that smoking cessation benefits all smokers, regardless of how few cigarettes they smoke." NBC News reports that smoking is the top cause of preventable death in the United States, and that it kills nearly half a million Americans every year, while it claims more than 6 million lives a year worldwide

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Liu et al.2011a) and two of which modified the cigarette filter (Branton et al.2011a,[b])