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Down-regulation of G6PD and GPX1 in transcriptional level altered the balance of GSSG and GSH

Co-localization of dehalogenase genes (e.g., reductive dehalogenases, haloacid dehalogenases) and mecJ homologs is common among related organisms (Table S4), and the gene cluster cmuABC for aerobic chloromethane utilization is 6 kb upstream and in the same orientation of a gene (IMG ID 650984269) encoding a putative chloride carrier/channel (ClC) protein, a protein family also implicated in acid-base homeostasis (Iyer et al., 2002)