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Six-to-12 months later, the patients were asked to recall if their pain had improved

Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [2]

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This phenomenon may be related to the fact that C3G-rich BBs has an extremely high oxygen radical absorbance capacity (ORAC), which may not be effective in alleviating oxidative stress because of the high dose

Meanwhile, the BNNS@PCL scaffold could maintain Schwann cell viability by modulating reactive oxygen species (ROS) level and restoring the energy metabolic balance [67]

Furthermore, the state of high ROS and low antioxidants in the tumor microenvironment (TME) drives immune cell dysfunction, leading to an immunosuppressive environment [8]