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this event is highly toxic to the white matter, membrane lipids, and DNA as well as leads to oxidative stress

doi: 10.1016/j.toxrep.2020.02.011 62 KumarC

Pernicious Anemia: New Insights from a Gastroenterological Point of View. 15.41 (2009): n.pag

Studies also show that estrogen and phytoestrogens influence epigenetic modifications, preserving the integrity of the genome and reducing the accumulation of age-related changes (Kovcs et al., 2020

Receptor Structure and Activation The IGF-1 receptor shares significant structural homology with the insulin receptor, existing as a heterotetrameric complex of two extracellular -subunits (which contain the ligand binding sites) and two transmembrane -subunits (which possess intrinsic tyrosine kinase activity in their intracellular domains)