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Gene Set Enrichment Analysis (GSEA) using TCGA cohort as testing cohort demonstrated that high M1 level significantly enriched gene sets related to cell proliferation, such as, MTORC1_SIGNALING, PI3K_AKT_MTOR_SIGNALING, MYC_TARGETS_v1, MYC_ TARGETS_v2 (Fig

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In other words, if you have chronic inflammation, you probably also have oxidative stress, and vice versa

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This compatibility may result in more predictable dose-response relationships and reduced potential for drug-drug interactions