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PloS One (2008) 3(11):e3731

Oxidative stress: a unifying paradigm in hypertension

50 The cytochrome P450 (CYP) enzymes in the endoplasmic reticulum and mitochondria, as well as the cyclooxygenases (COXs) and lipoxygenases (LOXs) involved in eicosanoid metabolism, contribute to ROS formation

The false discovery rate (FDR) for protein and peptide identification was set to 1%.Then, Pearson's correlation coefficient, principal component analysis (PCA), and relative standard deviation were used to evaluate the repeatability of samples from each group