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Pharmacologic Doses of Ascorbate Act as a Prooxidant and Decrease Growth of Aggressive Tumor Xenografts in Mice

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Thus, our results not only have potentially important mechanistic implications in how both the oxidative and antioxidant arms of redox homeostasis cooperate to regulate cell survival and death, but also provide a promising therapeutic strategy for cancer patients harboring oncogenic RAS that warrants further translational and clinical investigation

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Keep the affected area clean, elevate the limb when advised, and follow wound care instructions

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