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If you have been diagnosed with a B12 deficiency, your healthcare provider may recommend regular injections of vitamin B12

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Animal toxicology studies lasting up to 9 months (in non-human primates) found no significant organ toxicity, genotoxicity, or reproductive toxicity

Gonzalez- Rivas PA, Chambers M, Liu J

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In some countries hydroxocobalamin has completely replaced cyanocobalamin as first choice for vitamin B 12 therapy because it is retained in the body longer and can be administered at intervals of up to three months