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With limited information supporting SARS-CoV-2 infection of the brain, neuroinflammation appears to be a consequence of vascular disturbances and activation of inflammatory mediators (Constant et al., 2021

Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens

It is paramount that these probiotics efficacy, especially in reducing uremic toxins by modulating the gut microbiota, be further investigated in CKD patients