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Whereas most patients, including P3 and P4 in the current study, had a very similar and recognizable phenotype at birth, the siblings from family 1, and to a lesser extent P5, lacked most of the typical facial features at birth and in infancy, and they did not initially display pronounced skin fragility

[129] , methotrexate-loaded SLNs were prepared to enhance skin penetration and reduce keratinocyte proliferation

Torti SV, Manz DH, Paul BT, Blanchette-Farra N, Torti FM (2018) Iron and Cancer

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