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It takes approximately 4 to 5 half-lives for plasma concentrations to reach about 97% of their final steady-state value .8 Factors Influencing the Level of C ss While the time to reach steady state is dependent only on half-life, the level or magnitude of the steady-state concentration is determined by the balance between the dosing rate and the drug's clearance

It sounds plausible

Standard mineral salts can sometimes cause digestive discomfort or compete with other minerals (like copper or calcium) for absorption

[DOI] [PMC free article] [PubMed] [Google Scholar] 343.Ma, R

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