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Inflammation: Excessive sugar and unhealthy fats promote the release of pro-inflammatory cytokines in the brain, leading to neuroinflammation, which is linked to impaired memory and learning as well as an increased risk of neurodegenerative diseases

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*Correspondence: Rizhao Pang, [email protected] Zhang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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290 In HGPS cells, progerin destroys the interaction of lamin A/C with SIRT1 and SIRT6, affecting chromatin localization and deacetylase function

STORAGE Lyophilized 28 C protected from light, 12+ months Reconstituted 28 C, 14 days protected from light (limited by GHK-Cu component) PEER-REVIEWED EVIDENCE Kotani M, Detheux M, Vandenbogaerde A, et al