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The idea that restoring them to more youthful levels could keep the brain more flexible (sharper, more open to learn, with a better memory) has long interested scientists

Impaired autophagy and APP processing in Alzheimer's disease: the potential role of Beclin 1 interactome

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Alternatively, hypoxia was found to upregulate the ATP7A Cu-efflux transporter to reduce free Cu catalyzing the formation of reactive oxygen species 40

Pathological scoring was performed by two professional histologists blinded to the experimental groups, using a semi-quantitative scale (04) based on neuronal damage: 0, no damage (intact tissue structure)