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The intestinal tract, with its extensive blood supply, has a remarkable ability to renew the epithelial cell lining every 4-5 days [1]

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Accumulating evidence has verified that perturbation of Gln metabolism can significantly affect TCA cycle flux and tumor cell proliferation [48,49,50]

[48] Drugs that modify cytochrome P-450 enzyme are referred to as either inhibitors or inducers

doi:10.1016/S0731-7085(02)00351-5 Oaks JL, Gilbert M, Virani MZ et al (2004) Diclofenac residues as the cause of vulture population decline in Pakistan

J Pharmacol Exp Ther 315:879-887 Cover C, Liu J, Farhood A, Malle E, Waalkes MP, Bajt ML, Jaeschke H (2006) Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity