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Laboratory and clinical research indicate that GHK-Cu may stimulate Type I and Type III collagen production in dermal fibroblasts, with the strongest evidence from topical applications [2]

doi:10.1136/bcr-2013-009144

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10.1248/bpb.28.1321 83 OrangioG

4.3 GHK-Cus Possible Mechanism of Action 4.3 GHK-Cus Possible Mechanism of Action Despite decades of research, there is still a lack of unanimous agreement among researchers as to what allows GHK to produce so many diverse and positive biological effects