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Nevertheless, more systematic and comprehensive toxicological evidence is required to define the specific toxicity and the safe dosage range clearly

Figure 4a showed that rhGPx3 mutant was superimposed on U46C GPx4 mutant (PDB entry 2OBI) with a root mean square deviation of 2.87 , for 156 C-Alpha atoms

Our findings suggest that combining immunotherapy with therapies targeting GLO-1 may offer a synergistic therapeutic benefit

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