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suggested that using broadly neutralizing antibodies combined with LRAs and other immune modulators can harness the full capacities of antibodies during ART cessation.47,97 In this method, activation of gene expression by LRAs in the latent viral reservoirs led to an improved virus neutralization in the presence of broadly neutralizing antibodies.98 This strategy was very promising in Non-Human Primates (NHPs), and has been evaluated in two multiepitope vaccines clinical trials (i.e., NCT03619278 and NCT04357821)

Results: From Apr

TRPM4 is activated by increased intracellular ATP concentration and oxidative stress, but it is inhibited by intracellular ATP depletion (Nilius et al., 2004