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The effect on mitochondrial function supports its clinical use in other related conditions

Phytochemicals such as CGA, berberine, ganoderic acid, costunolide, piperine, and cardamonin not only reshape microbial communities but also influence their metabolites, gut barrier function, mucosal immunity, and even central nervous system signaling

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These receptors can be found throughout the brain, thyroid, adrenal glands, fat tissue, pancreas, and muscular heart tissue