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Structural brain changes and neuroticism in late-life depression: A neural basis for depression subtypes

10.1021/acs.accounts.9b00273

Similarly, in the pathophysiology of AAV, ROS is also known to play an important role in the development and exacerbation of AAV (Kitching et al., 2020

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Mechanistically, PCDHB14 is induced by p53, and increased PCDHB14 downregulates the expression of SLC7A11, which is mediated by accelerated p65 protein degradation resulting from PCDHB14 promoting E3 ubiquitin ligase RNF182-mediated ubiquitination of p65 to block p65 binding to the promoter of SLC7A11 (Liu Y