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The main effect of CB-839 was cytostatic, and no significant induction of apoptosis was observed

Hypertension 1995

10.1007/s12035-014-9070-5 166 TangY.ZuckerR

Molecular and cellular mechanisms linking chronic kidney disease and sarcopenia in aging: An integrated perspective

An effect on insulin resistance was also observed, which could be associated with the protective effect of hexokinase and -glycosidase activity and improved leptin resistance, suggesting that polyphenols may be the most critical factor in regulating insulin resistance and demonstrating that grape seed oil has a beneficial influence on the correlation between insulin resistance, energy metabolism, and hyperlipidemia