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A molecular sponge The researchers work on blocking cytokine storms grew out of a project that Zhang began 10 years ago to develop modified versions of membrane-embedded proteins

10.1155/2016/4323198 Oxid Med Cell Longev

Nature 183 , 746747 (1959)

Furthermore, several IDRs of LLPS-associated proteins contain arginine/glycine-rich (RGG-rich) regions in which charged amino acids, such as arginine/glycine, are disproportionately represented 27

Groups at Yale University tested this approach with their lipid nanoparticle (LNP)-mRNA vaccines encoding the full-length spike of SARS-CoV-2 Delta, SARS-CoV-1, and MERS-CoV

These cell lines were maintained in Dulbeccos Modified Eagles Medium (DMEM) (Thermo Scientific, #12100061)low glucose for HepG2 (Thermo Scientific, #31600091), supplemented with 1 % Penicillin/Streptomycin (P/S) and 10 % Fetal bovine serum (FBS) (Natocor)