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The PyMT is an extraordinarily penetrant oncogene (hundreds of tumor foci are simultaneously developed in each mammary gland), and Cre recombinase activity was not sufficient to delete the FASN gene in 100% of the breast epithelial cells (Fig

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M.CelineP.AriadnaR.PatriciaB.et al (2010)

Another excellent example comes from the interplay between LysRS and the HIV-1 Gag polyprotein

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