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Herniated Discs: The soft cushioning between vertebrae can bulge and press on nearby nerves, causing sciatica or other forms of leg numbness

NHS approach to B12 deficiency: NICE Clinical Knowledge Summaries recommend investigating B12 deficiency in patients presenting with macrocytic anaemia, unexplained neurological symptoms, or risk factors including pernicious anaemia, gastrectomy, malabsorption disorders, metformin use, proton pump inhibitors, or nitrous oxide exposure

Obviously, you shouldnt risk getting into an accident or being pulled over by the police and have to use theirs, but thats the situation many people find themselves in

MRI is used to look for associated conditions such as tumors, multiple sclerosis, or other secondary causes, and to assess whether a neurovascular contact (blood vessel compressing the nerve) is present and clinically relevant

And if you do go the AOD 9604 route

Additionally, research has explored NAD+'s role in acute neurological injuries such as stroke and traumatic brain injury using experimental models, with studies suggesting that rapid NAD+ depletion following brain injury contributes to neuronal death and that NAD+ restoration may be neuroprotective in research models