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Facts and questions Conditional deletion of Gss decreases the fertility of 8-month-old male mice Disrupted meiosis and ectopic acrosome are observed in 8-month-old S8/ Gss / mice Gss knockout in germ cells causes testis ferroptosis in older mice Both GSH and Fer-1 improve the fertility of 8-month-old S8/ Gss / male mice Similar content being viewed by others Introduction Male infertility is a multifactorial pathological condition that affects approximately 7% of the male population, and is primarily attributed to impaired spermatogenesis [1, 2]

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