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In the 2025 human IV infusion pilot, two adults receiving 10-20 mg doses showed no measurable changes in cardiac, hepatic, renal, thyroid, or glucose markers

Reports also indicate that compounded products are being combined with B vitamins or levocarnitine, additives that are claimed to bolster the drugs impact on weight loss, but may introduce new interactions impacting safety or effectiveness (Blum, 2023)

Treatments like Sculptra injections may include localized pain, swelling, or bruising, but these are generally mild and temporary