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26 Biochemical abnormalities commonly seen in patients with ASD include impaired methylation, sulphation capacities and low glutathione (GSH) redox capacity, all of which can potentially respond to B12 supplementation

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In cuprizone-induced demyelination LIF-deficient mice displayed more severe demyelination, increased loss of oligodendrocytes, and an impaired remyelination (Emery et al., 2006