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This improved understanding will enable more accurate interventions for stroke management, specifically targeting ferroptosis

These groups received intravenous treatments of oridonin, orid-liposome, orid-liposome-MAL, and TLR2 pep-orid-liposome at a dosage of 5 mg/kg (equivalent to the active ingredient of oridonin), with PBS serving as the control, administered every other day

The identified glutathione-related pathways provide potential therapeutic targets for alleviating oxidative stress-induced hippocampal injury in SAE, offering new insights for the clinical management of SAE-related neurological damage

The combination of redox buffering and inflammatory damping is a recurring theme across the compound's reported applications

[DOI] [PubMed] [Google Scholar] 76.Clasquin MF, et al

Alcohol Consumption Alcohol metabolism naturally generates oxidative stress, particularly in the liver