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Chen W, Yuan X, Li Z, Lu Z, Kong S, Jiang H, et al

doi: 10.3389/fphys.2015.00032 37 HrubyA.HuF

Above all, we confirmed that ECM1 in the secretomes of MenSCs alleviates liver fibrosis and inhibits the activation of HSC through the LRP1/AKT/mTOR and LRP1/FoxO1 signaling pathways

What makes it special is that it is designed to disrupt the interaction between FOXO4 and the tumor-suppressor protein p53 within senescent cells, thereby triggering programmed cell death (apoptosis) of those cells

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

Motor neurons can also be protected from mitochondrial dysfunction with the addition of EGCG in culture (Schroeder 2009)