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doi: 10.3390/jcm8040561

In addition, STAT3 can regulate the membrane expression of a variety of mitochondrial and cell membrane-related genes, thereby affecting mitochondrial function and cell membrane integrity, thereby affecting cell survival and death

This antitumor effect could be reversed by aspartate supplementation [26], reinforcing that the presence of other metabolites (in this case, another amino acid) in the TME can influence the effects of a single one in tumor biology

Under pathological conditions, the following three main mechanisms (oxidative stress, ER stress, and mitochondrial dysfunction) can affect drug metabolism of the liver, and drug metabolites further aggravate liver injury

In radioresistant GSCs, IR enhances H3K27ac enrichment at the CD47 promoter through HDAC7-dependent mechanisms, leading to increased CD47 expression and suppression of macrophage-mediated phagocytosis, thereby promoting immune evasion after radiotherapy (Sun et al., 2024b)

Rau bina Mi ty Nu bn mun tn dng ti a hm lng Glutathione t thc phm sng, cha nu chn, hy m bo ng rut ca bn khe mnh