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GPX7 can utilize the H 2 O 2 produced by Ero1 to accelerate the oxidative folding process of proteins in vitro and in vivo (Wang et al., 2014) (Figure 6)

Notably, these autoantibodies render patients highly susceptible to virus-caused diseases, including COVID-19 pneumonia [90], influenza pneumonia [91], Middle East respiratory syndrome (MERS) [92], and West Nile virus encephalitis [93]