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Estrogen and progesterone levels are at their lowest , and the hypothalamus responds by increasing secretion of gonadotropin releasing hormone (GnRH), which triggers pituitary production of gonadotropinsfollicle stimulating hormone (FSH) and luteinizing hormone (LH)

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Since GSH binding has been shown to stabilise PV 17,23 , we next used the PaSTRy assay 24 to demonstrate that GSH also shows a modest dose-dependent stabilisation of EV-F3 (Methods, Supplementary Fig

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The unbalanced regulation of two enzymes in the same cycle suggests that an alternative pathway exists to convert GSSG back to GSH