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2013;8(8):e70991

This Nrf2 activation may work in concert with the SAHH-dependent maintenance of the transsulfuration pathway, creating a multi-layered defense system wherein DJ-1 coordinately enhances both the synthesis (via transsulfuration) and the utilization (via Nrf2-target genes like GCLM) of glutathione

Their mitochondrial targeting appears to depend on scaffold or docking proteins, such as AKAP-12 [136] and docking protein 4 (Dok-4) [87]

governments far-reaching efforts to end HIV/AIDS include PEPFARs $85 billion investment in the global response to the disease since 2003

As a possibility, changes in membrane PEBP1-dependent lipid signals determine the dual function of autophagy in ferroptosis

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