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Sublingual doses of 5 mg (5000 mcg) of B12, daily for ten days, then 5 mg once per week for four weeks, then 5 mg monthly, have been found to be effective in restoring B12 levels in those with a deficiency

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But here's the encouraging reality: many causes of oligospermia are modifiable, and a growing body of research supports nutritional, lifestyle, and supplement-based strategies for improving sperm parameters, particularly when the cause is idiopathic (unexplained) or related to oxidative stress

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doi: 10.3389/fcvm.2025.1545231 Received 14 December 2024 Accepted 31 March 2025 Published 16 April 2025 Volume 12 - 2025 Edited by Xintian Cai, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, China Reviewed by Qiyao Xu, Nanjing University of Chinese Medicine, China Di Shen, People's Hospital of Xinjiang Uygur Autonomous Region, China Updates Copyright 2025 Liu, Yu, Lu, Liu, Chen and Li