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Variants in the CTLA4 gene may impair this inhibitory function, allowing autoreactive T cells to proliferate and attack the thyroid

Autoimmune and inflammatory conditions Patients with autoimmune conditions including lupus, rheumatoid arthritis, and Hashimoto thyroiditis have increasing access to GLP-1 therapy, and the anti-inflammatory mechanism provides specific rationale for this use

HBV infects hepatocytes through a specific interaction with the sodium taurocholate co-transporting polypeptide (NTCP) receptor on the hepatocyte surface

It is also the only stimulant FDA-approved to treat moderate-to-severe binge eating disorder in adults aged 18 and older

Nijhout HF, Reed MC, Anderson DA, Mattingly J, James SJ, Ulrich CM: Long-Range Allosteric Interactions between the Folate and Methionine Cycles Stabilize DNA Methylation Reaction Rate