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Mechanistically, GGsTop treatment led to an accumulation of serum tGSH and a depletion of cysteine in tumours (Fig

Glucose-6-phosphate dehydrogenase deficiency

doi:10.1016/j.coph.2007.06.003 Go YM, Ziegler TR, Johnson JM, Gu L, Hansen JM, Jones DP (2007) Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells