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In the present in vitro study, we determined the therapeutic effect of the semisynthetic bile acid analog and potent FXR agonist INT-787 in a human cholangiocyte cell line (H69) model of PSC

If a med goes through your liver, its taxing it, so you need a liver-loving nutrient like NAC or glutathione. Cohen lists the following classes of medications that are known to deplete Glutathione2: Acid blockers Analgesics Antacids Antibiotics Antivirals Tricyclic antidepressants Excess Body Fat Excess body fat triggers overproduction of several damaging proteins known to cause oxidative stress

Theoretically, these mechanisms contribute to better body composition and reduced muscle loss during weight loss

[DOI] [PubMed] [Google Scholar] 9.Hyun J., Han J., Lee C., Yoon M., Jung Y